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Extended protocol alcohol-free

Extended protocol alcohol-free

865.41 to renew 2 times

The extended protocol is scalable in its dosage. From the fourth week, the doses are maximum and constant until the 68th week.

This pack has sufficient quantities for 24 weeks, to be renewed twice.




Extended protocol alcohol-free (68 weeks)

Weeks 1 2 3 4-68 Total
Polygonum c. (per day in 3 times) 3 6 9 12 7406 capsules
Andrographis p. (per day in 3 times) 3 6 9 12 7406 capsules
Uncaria t. (per day in 3 times) 3 6 9 12 7406 capsules
Scutellaria b. (per day in 3 times) 1,5ml 2ml 2,5ml 3ml 1407 ml
Salvia m. (per day in 3 times) 1,5ml 2ml 2,5ml 3ml 1407 ml



This pack contains

The quantities provided in this pack correspond to a duration of 24 weeks, to be renewed twice.


Andrographis paniculata / Andrographis

5 boxes of 500 capsules

Andrographis paniculata is the main herb in the Buhner Protocol that has antitreponemal effect. It readily crosses the blood-brain barrier and accumulates in the tissues of the central nervous system – in the brain, spinal cord, cerebrospinal fluid. Because of its broad systemic effect on the body, it both protects the body from damage due to infection and kills the spirochetes where they nested and at the same time provides an overall systemic immune boost. It protects the heart muscle. When using this herb, you must remember that it can cause allergic reactions in the form of rashes (in about 1% of people). You should start with a small dose and gradually increase it while observing the body’s reaction. If such a reaction occurs, the herb should be discontinued.
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Uncaria tomentosa / Cat’s Claw

5 boxes of 500 capsules

Cat’s Claw (Lat. Uncaria tomentosa) is the primary herb in the Buhner protocol recommended for immune system regulation. This herb modulates the action of the immune system, increasing its strength when necessary and, if necessary, lowering excessive reactions. One of the most beneficial aspects of treating Lyme disease with Cat’s Claw is that it contributes to the growth of CD57+ cells which play an important role in the proper functioning of the immune system. When Lyme spirochetes are present in the body, they specifically inhibit the production of this subset of immune system cells. A low CD57 titer is a reliable marker in chronic Lyme disease, especially when antibiotic therapy has no effect. This ability to increase the CD57 cell count in Lyme disease patients is one of the reasons for the good results in the treatment of chronic or late Lyme disease. The use of Cat’s Claw helps to maintain high levels of CD57, which in turn helps to inhibit the progression of the disease. In addition, it has a specific anti-inflammatory effect in the treatment of joint and muscle pain in Lyme disease, reduces swelling and also has a positive effect on the nervous system. Cat’s claw must not be taken by people taking blood thinners. People who are scheduled for surgery must stop taking the herb 10 days before any planned surgery. Cat’s Claw should not be taken during treatment with drugs that inhibit gastric acid secretion because these can also inhibit the conversion of the herb to its active form in the stomach.
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Reynoutria japonica / Japanese Knotweed

5 boxes of 500 capsules

Japanese knotweed (Lat. Polygonum cuspidatum) is the primary herb included in the Buhner Protocol. Its role in the treatment of Lyme disease is significant. Japanese knotweed is a herb that exhibits antimicrobial activity, including activity against Lyme spirochetes as well as antiviral activity. It protects the integrity of the vascular endothelium which prevents the penetration of Borrelia bacteria and other co-infections, thus protecting against damage caused by them. It stimulates microcirculation, especially in the joints, heart, eyeballs, brain and skin and is therefore important in transporting active ingredients to areas affected by pathogenic microorganisms. The active ingredients of Japanese knotweed pass through the blood-brain barrier and affect the central nervous system where they have anti-spirochete and anti-inflammatory effects. Japanese Knotweed contributes to the reduction of inflammation in tissues and therefore reduces the impact of Borrelia bacteria in both joints and skin. It protects and improves heart function and reduces inflammation in tissues and is helpful for cardiac symptoms in Lyme disease such as palpitations, chest pain, shortness of breath and dizziness. Importantly, it lowers the body’s autoimmune response to Lyme disease. It helps to lower the strength of the Herxheimer reaction. This herb also reduces the production of reactive oxygen species in the brain and central nervous system. Japanese knotweed should not be used together with blood thinners. The use of this herb should be discontinued ten days before a planned surgical procedure.
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Scutellaria baicalensis / Chinese Skullcap

5 bottles of 100ml alcohol-free in a 1:1 dilution

Chinese skullcap (Baikal skullcap, Lat. Scutellaria baicalensis) acts as a modulator of the cytokine cascade, i.e. a regulator of inflammatory processes taking place in the nervous system. The spectrum of action of this herb is wide. In addition to its positive effects on the nervous system, Baikal skullcap has strong antiviral and antibacterial effects. It reduces the replication of pathogens, suppresses the expression of viral genes, interferes with the penetration of viruses, affects the functions of the immune system and has many other health-promoting properties. Chinese skullcap is also a very good synergist. Synergy means that the combination of two (or more) factors gives better results than the sum of the parts, i.e. the effect is intensified. So Chinese skullcap goes very well in combination with herbs but when you want to combine it with medicines, be sure to consult your doctor. Chinese skullcap can affect insulin and blood sugar levels, so people with type 1 diabetes should be cautious. The plant can interact with medications that lower blood pressure.
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Salvia miltiorrhiza / Red sage

5 bottles of 100ml alcohol-free in a 1:1 dilution

Salvia (Red sage, Lat. Salvia miltiorrhiza) is a herb that, like Chinese skullcap is used as a modulator of the cytokine cascade, i.e. it regulates the complex inflammatory process triggered during infections, including those taking place in the nervous system. In addition, it protects the integrity of the lymphatic endothelium, limiting cell invasion by pathogens or the harmful effects of cytokines. We have written about the importance of modulating the cytokine cascade in the “Practical Guide – Application of Herbal Therapies for Lyme Disease and Coinfections”. An important property of Salvia is the protective function of the Golgi apparatus of nerve cells. The Golgi apparatus is an organelle found in the cell that serves to chemically modify the substances produced by the cell, sort them and distribute them within the cell. The Golgi apparatus of nerve cells is damaged in the course of Lyme and tick-borne diseases. It is also damaged in neurological diseases such as multiple sclerosis, Parkinson’s disease or Alzheimer’s disease. If the Golgi apparatus is damaged in the course of a tick- borne disease, symptoms similar to those of the above-mentioned neurological diseases can develop. Please note the great importance of Salvia in the context of tick-borne diseases. This herb should already be added as one of the primary herbs in the treatment of Lyme disease. If you have used the Buhner Protocol as a basic core therapy and you have increased neurological problems then you can increase the dose of Salvia by up to 2-3 times. This herb is safe to use. If you have been using herbs other than Buhner’s herbs as the core of therapy, and you have increased neurological symptoms, then think about introducing this herb as an adjunct to therapy.
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Usage precautions


  • Andrographis paniculata: can cause allergic reactions in the form of skin rashes (in about 1% of people). Not to be used during pregnancy. Inhibits progesterone production, should not to be used by women when trying to conceive. May cause mild constipation. Should not be used in active gall bladder disease.
  • Uncaria tomentosa: because of the immune-stimulating actions, do not use if you have had an organ transplant or are using immunosuppressive drugs. Do not use if you are using blood-thinning medications or are scheduled for surgery. Do not use if you are trying to become pregnant or are pregnant. Caution should be exercised if you have low blood pressure.
  • Polygonum cuspidatum: bothersome side effect that seems to occur in about 1 percent of the people using the herb is loss of taste. Side effects and quite rare are primarily gastrointestinal in nature : dry mouth, bitter taste in mouth, nausea, vomiting, abdominal pain, and diarrhea (rare). Contraindicated in pregnancy.
  • Scutellaria baicalensis : Type 1 diabetics should exercise strong caution with the herb as it can affect insulin and blood sugar levels. It should not be used during pregnancy. Caution should be exercised if you are taking pharmaceuticals as it can increase the bioavailability of the drugs, thus increasing their impacts. It may interact additively with blood-pressure-lowering drugs.
  • Salvia miltiorrhiza : This herb is safe to use.

In addition to the protocol

Although the basic protocol is sufficient on its own, it is strongly recommended to add the collagen support to it in order to reconstitute it.


Collagen support


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